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Spine loss in depression impairs dendritic signal integration in human cortical microcircuit models

Yao HK, Mazza F, … Sibille E, Hay E

bioRxiv 2024 preprint

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Deriving connectivity from spiking activity in biophysical cortical microcircuits

Moghbel F, Hassan MT, Guet-McCreight A, Hay E

bioRxiv 2024 preprint

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Therapeutic dose prediction of α5-GABA receptor modulation from simulated EEG of depression severity

Guet-McCreight A, Mazza F, ... Sibille E, Hay E

bioRxiv 2024 preprint

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EEG biomarkers of α5-GABA positive allosteric modulators in rodents

Mazza F, Guet-McCreight A, ... Sibille E, Hay E

bioRxiv 2024 preprint

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Linking reduced prefrontal microcircuit inhibition in schizophrenia to EEG biomarkers in silico

Rosanally S, Mazza F, Yao HK, Hay E

bioRxiv 2024 preprint

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In-silico testing of new pharmacology for restoring inhibition and human cortical function in depression

Guet-McCreight A, ... Valiante TA, Sibille E, Hay E

Communications Biology 2024; 7, 225 article

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In-silico EEG Biomarkers of reduced inhibition in human cortical microcircuits in depression

Mazza F, Guet-McCreight A, Valiante TA, Griffiths JD , Hay E

PLoS Comput Biol 2023; 19(4): e1010986 article

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Age-dependent increased sag amplitude in human pyramidal neurons dampens baseline cortical activity


Guet-McCreight A, Chameh HM, Mahallati S, Wishart M, Tripathy SJ, Valiante TA, Hay E

Cerebral Cortex 2023; Volume 33, Issue 8, 15 April article

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An in vitro whole-cell electrophysiology dataset of human cortical neurons

Howard D,... Hay E, Valiante TA, Tripathy SJ

GigaScience 2022 article

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Reduced inhibition in depression impairs stimulus processing in human cortical microcircuits

Yao HK, Guet-McCreight A, Mazza F, ... , Valiante TA, Sibille E, Hay E

Cell Reports 2022; 38 (2) article


Orientation processing by synaptic integration across first-order tactile neurons

Hay E, Pruszynski JA

PLoS Comput Biol. 2020 Dec 2; 16 (12): e1008303  article


Multiregional integration in the brain during resting-state fMRI activity

Hay E, Ritter P, Lobaugh NJ, McIntosh AR

PLoS Comput Biol. 2017 Mar 1; 13 (3): e1005410 article


A theoretical view of the neuron as an input-output computing device

Hay E, Gidon A, London M, Segev I

Dendrites. 3rd edition, Oxford University Press. 2016, 439-464

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Reconstruction and simulation of neocortical microcircuitry

Markram H, ..., Hay E, et al.

Cell. 2015 Oct 8; 163 (2): 456-92 article

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Dendritic excitability and gain control in recurrent cortical microcircuits

Hay E, Segev I

Cereb Cortex. 2015 Oct; 25 (10): 3561-71 article

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​​​​​Preserving axosomatic spiking features despite diverse dendritic morphology

Hay E, Schurmann F, Markram H, Segev I

J Neurophysiol. 2013 Jun; 109 (12): 2972-81 article

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​​​​Models of neocortical layer 5b pyramidal cells capturing a wide range of dendritic and perisomatic active properties

Hay E, Hill S, Schurmann F, Markram H, Segev I

PLoS Comput Biol. 2011 Jul; 7 (7): e1002107 article

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